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This content is for candidates who took the COMLEX-USA Level 2-CE before June 2019. Candidates taking the COMLEX-USA Level 2-CE beginning June 17, 2019 can view the new documentation here.

Assessment of Fundamental Clinical Sciences


Examination Description

COMLEX-USA Level 2-Cognitive Evaluation (CE) is a problem- and symptom-based assessment, administered in a time-measured environment that integrates the fundamental clinical science disciplines (see listing below) and other areas of medical knowledge relevant to solving clinical problems and promoting and maintaining health in providing osteopathic medical care to patients, principally in the supervised (graduate medical education) setting.

COMLEX-USA Level 2-CE · Clinical Sciences Disciplines

  • Emergency Medicine
  • Family Medicine
  • Health Promotion and Disease Prevention
  • Internal Medicine
  • Neuromusculoskeletal Medicine
  • Obstetrics/Gynecology
  • Osteopathic Principles
  • Pediatrics
  • Psychiatry
  • Surgery

The examination consists of two computer-based test sessions of four hours each taken on one day and contains a total of approximately 400 test questions (items) related to diverse clinical presentations. Test questions are predominantly in the single best answer, multiple choice or extended matching item formats, with some novel test items involving audio-visual components designed to assess an expanded physician competency subset. Examples of test item types expected to be encountered in Level 2-CE can be found under Practice Exams, and the practice examination begins with a tutorial.


Passing Level 2-CE indicates that the candidate has demonstrated competence in fundamental clinical science disciplines required to solve clinical problems and manage patient presentations in a supervised clinical practice setting, to enter into graduate medical education, and to prepare for lifelong learning.

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