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Assessment of Fundamental Clinical Sciences for Osteopathic Medical Practice

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Examination Description

The COMLEX-USA Level 2-Cognitive Evaluation (Level 2-CE) is a one-day, computer-based assessment that integrates application of knowledge in clinical and foundational biomedical sciences with other physician competencies related to the clinical care of patients and promoting health in supervised clinical settings.

Competency domains assessed include application of osteopathic medical knowledge, osteopathic patient care, osteopathic principles and practice, communication skills, systems-based practice, practice-based learning and improvement, professionalism, and ethics.

COMLEX-USA Level 2-CE · Clinical Science Disciplines

The examination, taken in a secure, time-measured environment, consists of two computer-based test sessions of four hours each. It contains 352 test questions related to diverse clinical and patient presentations and seven defined competency domains for osteopathic medical practice. Test questions are single-best-answer multiple-choice format with some test items involving audio-visual components designed to assess an expanded physician competency subset. Examples of test item types expected to be encountered in Level 2-CE can be found under Practice Exams.

An updated percentile score converter for COMLEX-USA Level 2-CE is now available.


Passing COMLEX-USA Level 2-CE indicates that the candidate has demonstrated competence in the clinical sciences and related physician competency domains for osteopathic medical care of patients as required to enter into supervised graduate medical education settings and to continue lifelong learning.

Road to DO Licensure

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