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COMLEX-USA

The Pathway to Osteopathic Medical Practice & Licensure in the United States

The Comprehensive Osteopathic Medical Licensing Examination of the United States (COMLEX-USA) is a three-level, national standardized licensure examination designed for licensure for the practice of osteopathic medicine. The COMLEX-USA Examination Series is designed to assess osteopathic medical knowledge, knowledge fluency, clinical skills, and other competencies essential for practice as an osteopathic generalist physician. It is also a graduation requirement for attaining a DO (Doctor of Osteopathic Medicine) degree from colleges of osteopathic medicine in the United States, and for entry into and promotion within graduate medical education (residency) training programs.

What is COMLEX-USA?

Examination Series Sequence

The COMLEX-USA examination series follows a progressive sequence broken into three levels described below. Osteopathic medical students and residents are deemed licensure exam “candidates” as referred to throughout this site and must be verified eligible to take each level of COMLEX-USA by their college of osteopathic medicine dean or residency program director, meet the requirements and take the exams in sequence, passing each level before advancing to the next.

COMLEX-USA LEVEL 1

Computer based, application of osteopathic medical knowledge concepts related to foundational sciences, patient presentations and physician tasks

COMLEX-USA LEVEL 2-CE

Computer based, application of osteopathic medical knowledge concepts related to clinical sciences, patient presentations and physician tasks

COMLEX-USA LEVEL 3

Two-day computer-based, application of osteopathic medical knowledge concepts related to clinical sciences, patient safety and independent practice, foundational competency domains and clinical presentations


All candidates must read NBOME’s COMLEX-USA Bulletin of Information (BOI) and agree to the Terms and Conditions before scheduling any COMLEX-USA examination. The BOI is a comprehensive guide to COMLEX-USA examinations, including but not limited to the Terms and Conditions, examination descriptions, eligibility requirements, scheduling, administration, security, scoring and transcripts.

Road to DO Licensure

A whole new program for osteopathic medical students and residents.

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